The Subscription ED Treatment That 2 Million Men Already Use

By SkinCareSupplements.com Research & Editorial Team · Updated September 11, 2026

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Board-certified clinicians, personalized compound prescriptions, and ongoing dose optimization — entirely online.

For men dealing with ED, the traditional path is uncomfortable at every step: scheduling an appointment, sitting in a waiting room, having an awkward face-to-face conversation, then picking up a prescription at a pharmacy where anyone might see you. It is no wonder that an estimated 75% of men with ED never seek treatment at all.

Even when men do get a prescription, the standard approach is often one-size-fits-all. A generic 50mg sildenafil tablet. If it works, great. If it does not work well enough, or if the timing is wrong, or if there are side effects — figuring out the right adjustment often means another office visit, another co-pay, another uncomfortable conversation.

The telehealth model has fundamentally changed this. But not all telehealth ED services are created equal. Most simply prescribe a single generic medication and ship it. They do not customize. They do not follow up. They do not optimize.

Why Keeps Powerhouse stood out

Keeps Powerhouse stood out because it goes beyond the basic telehealth prescription model. Their board-certified clinicians do not just prescribe a standard medication — they create compound prescriptions that combine multiple active ingredients (tadalafil, vardenafil, and apomorphine) in sublingual tablets customized to each patient’s profile.

The key differentiator is ongoing optimization. The clinician adjusts your formulation and dose based on your feedback until the results meet your expectations. This is not a one-and-done prescription — it is an iterative process managed by a specialist who focuses exclusively on men’s sexual health.

What we found

Multi-compound sublingual formula. Combines tadalafil, vardenafil, and apomorphine in one rapid-dissolve tablet — targeting both desire and physical response simultaneously.

Personalized dose optimization. Board-certified clinicians adjust your formula until results meet your expectations. Not a one-size-fits-all prescription.

Entirely online process. 60-second health questionnaire, physician review, prescription shipped in discreet unmarked packaging. No office visits required.

Multiple treatment options. Choose between Powerhouse (comprehensive), Quicky (fast-acting), Weekend (long-lasting), or Combo based on your needs.

What’s in it

Keeps Powerhouse combines Tadalafil (a PDE5 inhibitor providing extended 24-36 hour window of effectiveness), Vardenafil (a PDE5 inhibitor known for rapid onset), and Apomorphine (a dopamine agonist that works on the brain’s arousal center). The compound is formulated as a sublingual rapid-dissolve tablet for faster absorption compared to traditional oral medications. Dosing is customized by the prescribing clinician. Alternative formulations include Quicky (fast-acting, 4-6 hours), Weekend (active up to 36 hours), and Combo options.

What we like — and what we don’t

The bottom line

Keeps has built what the traditional ED treatment process should have been all along: personalized, private, and optimized over time. The compound prescription approach means you are not stuck with a single generic option. The clinician works with you until the formula and dose deliver the results you want.

At $1/day, it is priced competitively with basic generic sildenafil, while offering significantly more: compound formulations, multiple treatment options, ongoing optimization, and a care team focused exclusively on men’s health. The 60-night guarantee lets you evaluate the service with no financial risk. For men who want a comprehensive, private solution they do not have to think about — this is the service we would recommend.

Individual results may vary. This content is for informational purposes and is not intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before starting any new supplement. These statements have not been evaluated by the FDA.